24 April 2015

The genome of a Woolly Mammoth


Helen Regan has a Time article about a scientific breakthough:
An international team of scientists has sequenced the whole genome of the woolly mammoth, a breakthrough that could help our understanding of why these hairy cousins of the elephant went extinct. The last surviving population died out the Arctic island called Wrangel off the coast of Russia some four thousand years ago, six thousand years after their relatives disappeared from mainland Siberia, reports The Los Angeles Times.
The researchers, who published their findings in the journal Current Biology recently, compared the DNA from two woolly mammoths that had been frozen in permafrost: a juvenile male that lived in northeastern Siberia nearly fifty thousand years ago and a male from Wrangel Island that lived some four thousand years ago. “From a single individual you can get information about the entire population,” said co-author of the study, Eleftheria Palkopoulou.
Using the stem cells of a modern African elephant as the test, the team found that the population of woolly mammoths marooned on Wrangel Island was so small that the beasts had become inbred.
Though climate change and human intervention are often touted as factors, scientists aren’t entirely sure what caused the mammoth to die out, and researchers wanted to see whether genetic features could be responsible.
The genetic data also showed there were two major population declines, one some three hundred thousand years ago and another around twelve thousand years ago, at the end of the last Ice Age.
But scientists warn the lack of diversity in DNA from the Wrangel population does not necessarily mean genetics caused the mammoth to die out, and a closer examination of the data could help them understand how these creatures evolved and what sets mammoths apart from modern elephants.
Rico says let's hope no one decides to try making one now...

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